Why We're Different

Our Unique Approach to Quality

Our Commitment to Excellence

We believe in empowering researchers to achieve breakthroughs. Whether exploring new frontiers in regenerative science or validating innovative methodologies, MethusBio is your trusted partner for reliable and ethically sourced biologics.

Quality Assured
Validated Results
Industry Leading

Our Commitment

Random, Unannounced Testing

Vials are tested without warning. If a lab's "validated" batch fails, we don't distribute their products.

Real Post-Thaw Viability

Viability is verified after freezing and shipping, so you see the real performance you'll get.

Licensing & Due Diligence

We check every lab's paperwork, equipment, and compliance, so you don't have to.

Proper Cold Chain Logistics

We insist on correct LN2 shipping temperatures. If they can't handle it, they won't handle your cells.

Products & Services

Human Umbilical-Cord Derived Cell Products

Products & Services

Specialized Support Products

Cryopreservation Media

  • Optimized for ultra-low temperature storage of biologics and cells.
  • Validated for compatibility with stem cells and other sensitive cell types.

Cell Culture Media

  • Specialized formulations designed to maintain cell viability and support expansion in controlled laboratory environments.

Biologics Enhancements

  • Additives such as growth factors, cytokines, and peptides to support advanced cellular research.

Custom Solutions

MethusBio offers customized services to meet the unique needs of researchers and labs:

  • Bulk Orders: Tailored for labs requiring large quantities of consistent research-grade products.
  • Trial Programs: Sample-sized offerings of new products for initial testing in unique research settings.
  • Consultation Services: Technical guidance and troubleshooting to ensure optimal product performance.

Research

Research Resourced

FAQs

Common Questions About Our Products

  • Independent Post-Thaw Viability Testing – Many labs report viability pre-freeze, but post-thaw performance can be drastically different. We ensure accurate, independent testing.
  • Flow Cytometry & Biomarker Validation – Labs use internal testing, but without incentives to be honest. We verify passage number, cell phenotype, and viability with third-party flow cytometry.
  • Cold Chain Tracking & Compliance – Handling mistakes and temperature fluctuations degrade cells. We enforce continuous temperature monitoring and ensure proper logistics.
  • Risk Mitigation for Clinics & Researchers Internationally – Stem cell compliance is complex, and improper sourcing has serious legal and safety risks. We help clients navigate these challenges while maintaining ethical sourcing.

Stem cells are shipped cryopreserved in liquid nitrogen vapor phase (≤−150°C) using a validated dry shipper. This maintains cell viability during transit. Package includes:
  • Cryobox or cryobag
  • Dry shipper with temp logger
  • Shipping manifest

We use liquid nitrogen (LN2) to keep hUC-MSCs well below the glass phase, or vitrification transition zone, at −150°C, preventing ice crystal formation and metabolic activity. This preserves cell viability, potency, and regulatory compliance during storage and shipping.

Passage number refers to how many times a cell culture has been subcultured or transferred to a new vessel during laboratory expansion. Each time the cells are split and replated to continue growing, the passage number increases (e.g., P0, P1, P2, etc.).

This number matters because it reflects the replicative age of the cells. Over time, high passage numbers can lead to changes in cell behavior, function, and genetic stability. For therapeutic and research use, maintaining a low passage number ensures high-quality, functional, and consistent cells.

Early-Passage MSCs (P1–P4):

  • High proliferation potential
  • Low senescence
  • Strong differentiation capacity
  • Potent immunomodulatory function

Mid-Passage MSCs (P5–P6):

  • Decline in proliferation
  • Emerging senescence markers
  • Reduction in therapeutic potency

Late-Passage MSCs (P7+):

  • Reduced differentiation ability
  • Weakened immunomodulatory effects
  • Increased risk of genetic instability

Contact

Contact Us

Address

Ensenada, Baja California, C.P. 22760, México

Call Us

+52 646 173 1431

Email Us

info@Methusbio.com

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